Comparison of hyperfibrinolysis in trauma and non-trauma patients

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Comparison of hyperfibrinolysis in trauma and non-trauma patients

Methods We conducted an observational, retrospective study in two academic trauma centers from a French university institution. All patients diagnosed with HF on rotational thromboelastometry (ROTEM) between 2010 and 2014 were included. Demographic and clinical parameters, standard laboratory and ROTEM results were collected. HF diagnosis was established when the 60 minute clot lysis index (CLI...

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Trauma-induced coagulopathy (TIC) has been considered for a long time as being due to depletion of coagulation factors secondary to blood loss, dilution and consumption. Dysfunction of the remaining coagulation factors due to hypothermia and acidosis is assumed to additionally contribute to TIC. Recent data suggest that hyperfibrinolysis (HF) represents an additional important confounder to the...

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ژورنال

عنوان ژورنال: Intensive Care Medicine Experimental

سال: 2015

ISSN: 2197-425X

DOI: 10.1186/2197-425x-3-s1-a851